We comply with the HONcode standard for trustworthy health information -, Burning, stinging, or discomfort when medicine is applied, itching, redness, swelling, or other sign of the eye or eyelid irritation, redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid, Blistering, burning, crusting, dryness, or flaking of the skin, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, sores, ulcers, or white spots in the mouth or on the lips, increased sensitivity of the eyes to sunlight, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, severe redness, soreness, or swelling of the skin. It may be used when a beta blocker, like timolol, is not sufficient alone. Consult your doctor before taking Trusopt if pregnant or breastfeeding. Trusopt (dorzolamide) is an ophthalmic solution used to treat glaucoma. Dorzolamide is applied to the eye and is used off label to treat glaucoma (increased eye pressures). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Dorzolamide and timolol may cause other side effects. The Cosopt (Dorzolamide / Timolol) FDA package insert doesn’t have numbers about how common side effects are. Along with its needed effects, a medicine may cause some unwanted effects. Dorzolamide ophthalmic (eye) drops is used to treat increased pressure in the eye caused by open-angle glaucoma or a condition called hypertension of the eye. Side Effects What are the side effects of Dorzolamide Ophthalmic (Trusopt)?. Filter group. If a negative reaction occurs, please call your veterinary office. Common side effects of Trusopt include eye irritation, eye burning, eye stinging, eye discomfort, bitter taste, and allergic eye reaction or eye inflammation (superficial punctate keratitis). Before taking dorzolamide, tell your doctor: If you are allergic to dorzolamide; any part of this medicine; or any other drugs, foods, or substances. All rights reserved. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Cerner Multum, Inc. "UK Summary of Product Characteristics." Dorzolamide and timolol ophthalmic (eye) drops is used to treat increased pressure in the eye caused by open-angle glaucoma or a condition called hypertension of the eye. Dorzolamide, sold under the brand name Trusopt among others, is a medication used to treat high pressure inside the eye including glaucoma. Merck & Co, Inc, West Point, PA. 3. If you experience any of the following symptoms, call your doctor immediately: Applies to dorzolamide ophthalmic: ophthalmic solution. Risks and risk factors. These side effects may go away during treatment as your body adjusts to the medicine. Severe skin reactions also have been reported. To investigate the effects of topical dorzolamide 2% q8h and brinzolamide 1% q8h, administered either alone (A and B, respectively) or in combination with topical timolol 0.5% q12h (C and D, respectively), on the circadian pattern of intraocular … Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: The most commonly reported side effects were ocular burning, stinging, or discomfort, and bitter taste. Untoward side effect: A dorzolamide allergy refers to an untoward reaction to the chemical dorzolamide and results generally in conjunctival and eyelid allergic manifestati ... Read More 1 doctor agrees Conjunctivitis and lid reactions reported with chronic administration (may resolve with discontinuation of drug therapy Many of these reactions had the clinical appearance and course of an allergi c- t ype reaction that resolved upon discontinuation of drug therapy. Get emergency medical help if you have signs of an allergic reaction … Potential side effects of Dorzolamide 2% Ophthalmic Solution: This medication may cause the eye to sting for a short period after application This medication can cause local irritation resulting in redness of the tissues surrounding the eye If these symptoms persist … You will find a full list in the manufacturer's information leaflet supplied with the drops. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Download Practo app & get your medicines home delivered. Eye Itching; Dorzolamide has been poorly studied in children with glaucoma. Blurred eyesight. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. Dorzolamide is applied to the eye and is used off label to treat glaucoma (increased eye pressures). Dorzolamide is used to reduce the pressure inside the eye for people with open-angle glaucoma or ocular hypertension (increased pressure in the eye). Objective. You may report them to the FDA. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Both eye conditions are caused by high pressure in your eye and can lead to pain from pressure … Last Updated on Wed, 06 Jan 2021 | Side Effects of Drugs Skin Topical dorzolamide caused severe periorbital dermatitis after an average exposure time of 20 weeks in 14 patients (7c). Available for Android and iOS devices. Certain side effects of Dorzolamide that one may experience are bad mouth taste, light sensitivity, production of more tears, dryness of the eyes, burning or irritation in the eyes and blurry vision. Dorzolamide/timolol, sold under the brand name Cosopt among others, is a medication used to treat high pressure inside the eye including glaucoma. Eye irritation. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for DORZOLAMIDE. The table below contains the most common ones associated with dorzolamide. Although the risk of serious side effects is low when dorzolamide and timolol is used in the eyes, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream. Continue to use dorzolamide ophthalmic and talk to your doctor if you experience: burning, stinging, itching, or watering of the eye blurred vision sensitivity of the eye to sunlight a change in taste headache fatigue a rash nausea. Therefore, dorzolamide should not be administered to patients with allergies to sulfonamides, and it can cause some of the side effects of sulfonamides. Tell your doctor if any of these symptoms are severe or do not go away: stinging, burning, or discomfort in the eye after inserting the drops; bitter taste after inserting the drops; sensitivity to light; upset stomach; vomiting; Some side effects can be … Call your doctor if you have any unusual problems while using this medication. Dorzolamide is used to reduce the pressure inside the eye for people with open-angle glaucoma or ocular hypertension (increased pressure in the eye). Drug information provided by: IBM Micromedex. No information currently available. Side effect rates for Trusopt (Dorzolamide) 0 reports. May cause redness, itching, swelling, or other signs of eye irritation in animals allergic to dorzolamide. Common side effects of Cosopt include: Timolol + Dorzolamide may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. Side Effects Temporary blurred vision , temporary burning/stinging/ itching /redness of the eye , watery eyes , dry eyes , sensitivity of eyes to light, bitter taste, or headache may occur. Systemic Exposure. Side effects; Storage; What is dorzolamide used for? Cosopt (dorzolamide hydrochloride-timolol maleate) is a combination of a carbonic anhydrase inhibitor and a beta-blocker that reduces pressure in the eye and is used to treat certain types of glaucoma and other causes of high pressure inside the eye. All rights reserved. DORZOLAMIDE; TIMOLOL is used in the eye to treat open-angle glaucoma and high pressure in the eye. Dorzolamide ophthalmic may cause your pet’s eyes to become more sensitive to light. O 0. Cosopt is available in generic form. Possible Side Effects Dorzolamide ophthalmic stings when placed in the eye. If experienced, these tend to have a Severe expression. Dorzolamide has minimal or no effect on pulse rate or blood pressure. It is used as an eye drop. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Dorzolamide is available as an eye drop that is usually given 3 times per day in the affected eye. It is used as an eye drop. In reproduction studies of dorzolamide hydrochloride in rats, there were no adverse effects on the reproductive capacity of males or females at doses of 15 and 7.5 mg/kg/day, respectively. Portions of this document last updated: Aug. 01, 2020. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. If a negative reaction occurs, please call your veterinary office. Dorzolamide and timolol may cause side effects. Also, since blurred vision may be a sign of a side effect that needs medical attention, check with your doctor if it continues. Both eye conditions are caused by high pressure in your eye and can lead to pain from pressure … Dorzolamide HCI/Timolol Maleate Ophthalmic Solution contains Dorzolamide, a sulfonamide, and Timolol Maleate, a beta-adrenergic blocking agent; and although administered topically, is absorbed systemically. Tell your doctor if any of these symptoms are severe or do not go away: taste changes (bitter, sour, or unusual taste) eye burning or stinging; itchy eyes; dry eyes; eye tearing; dizziness; Some side effects can be serious. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis Mayo Clinic does not endorse companies or products. Everyone Men Women. Dorzolamide is used to treat glaucoma. vitamins, herbal supplements, etc. Visit your doctor or health care professional for regular checks on your progress. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Less serious side effects may be more likely to occur. Upon its approval a few years ago as the first topical CAI, it was a welcome addition to the glaucoma therapeutic armamentarium because of significant systemic side effects associated with oral … latanoprost ophthalmic, epinephrine ophthalmic, timolol ophthalmic, Xalatan, brimonidine ophthalmic, Lumigan, Combigan. Check with your doctor immediately if any of the following side effects occur while taking dorzolamide ophthalmic: Get emergency help immediately if any of the following symptoms of overdose occur while taking dorzolamide ophthalmic: Some side effects of dorzolamide ophthalmic may occur that usually do not need medical attention. Dorzolamide-Timolol Drops Side Effects by Likelihood and Severity COMMON side effects. Action Description: Dorzolamide reversibly inhibits carbonic anhydrase resulting in reduction of hydrogen ion secretion at renal tubule and increased renal excretion of Na, K, bicarbonate, and water, thus decreasing the production of aqueous humor. Trusopt (dorzolamide ophthalmic)." Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort. Call your doctor for medical advice about side effects. The Cosopt (Dorzolamide / Timolol) FDA package insert doesn’t have numbers about how common side effects are. Side Effects & Adverse Reactions. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Long-term use of Lumigan (bimatoprost) Changes to eyelashes. Trusopt is available in generic form. Other important, but less common side effects include: These side effects may go away during treatment as your body adjusts to the medicine. Dorzolamide is used in the treatment of increased pressure in the eye and open-angle glaucoma, a condition which may lead to eventual vision loss. It is used as an eye drop. Trusopt (dorzolamide) is a carbonic anhydrase inhibitor that reduces the amount of fluid in the eye, which decreases pressure inside the eye, used to treat open-angle glaucoma and other causes of high pressure inside the eye. See below for a comprehensive list of adverse effects. Copyright © 2021 IBM Watson Health. Check with your doctor immediately if any of the following side effects … Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. Sandoz Dorzolamide: Dorzolamide belongs to the family of medications called carbonic anhydrase inhibitors. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.For commercial use or customized versions, please contact biobyte solutions GmbH.. Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only. Side effects other than those listed here may also occur. Common side effects of Trusopt include eye irritation, eye burning, eye stinging, eye discomfort, bitter taste, and allergic eye reaction or eye inflammation … Advertising revenue supports our not-for-profit mission. Serious side effects are unlikely when dorzolamide is used in the eyes, but can occur if the medicine is absorbed into your bloodstream. All currently selected. Drug information provided by: IBM Micromedex. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for DORZOLAMIDE. Absorbed systemically, potential risk of adverse effects similar to those for systemic sulfonamides (eg, Stevens-Johnson synd, blood dyscrasias, fulminant hepatic necrosis, and toxic necrolysis) may occur with ophthalmic use. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Dorzolamide eye drops may cause side effects. If these side effects do not go away or become more severe get in touch with your medical provider immediately and seek treatment. The lowest GoodRx price for the most common version of dorzolamide / timolol is around $13.75, 85% off the average retail price of $94.10. Medscape - Indication-specific dosing for Trusopt, (dorzolamide), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. It is also available as the combination dorzolamide/timolol.. Common side effects include eye discomfort, eye redness, taste changes, and blurry vision. Side Effects What are the side effects of Dorzolamide Ophthalmic (Trusopt)?. What should I watch for? Dorzolamide, one of the active ingredients, is a sulfonamide drug and therefore has the potential to cause severe allergic reactions. 2. Along with their useful effects, eye drops can cause unwanted side-effects although not everyone experiences them. Darker eye color and eyelids. Along with its needed effects, dorzolamide ophthalmic may cause some unwanted effects. It is also available as the combination dorzolamide/timolol.. Common side effects include eye discomfort, eye redness, taste changes, and blurry vision. Trusopt (dorzolamide) is a carbonic anhydrase inhibitor that reduces the amount of fluid in the eye, which decreases pressure inside the eye, used to treat open-angle glaucoma and other causes of high pressure inside the eye. [Ref], Very common (10% or more): Superficial punctate keratitis (up to 15%), burning/stinging, Common (1% to 10%): Tearing, conjunctivitis, eyelid inflammation, eye itching, eyelid irritation, blurred vision, Rare (less than 0.1%): Irritation, pain, eyelid crusting, transient myopia, corneal edema, ocular hypotony, choroidal detachment following filtration surgery[Ref], Very common (10% or more): Ocular allergic reaction (10%), Rare (less than 0.1%): Signs and symptoms of local reactions (palpebral reactions) and systemic allergic reactions including angioedema, urticaria, pruritus, rash, shortness of breath, bronchospasm[Ref], Uncommon (0.1% to 1%): Contact dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, Very common (10% or more): Biter taste (up to 25%), Rare (less than 0.1%): Throat irritation, dry mouth[Ref], Common (1% to 10%): Asthenia/fatigue[Ref], 1. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Common side effects include stinging sensation, eye redness, watery eyes, and light sensitivity. In a prospective study of 2% dorzolamide tds in children aged 1 week to under 6 years the most common drug-related adverse effects were ocular hyperemia (5.4%) in those aged 2 years or under and ocular burning/stinging (12%) in those from aged 2–6 years [46]. Age. However, many people have no side effects or only have minor side effects. "Product Information. Dorzolamide does not cause pupillary constriction and reduces intra-ocular pressure without side effects such as night blindness, accommodative spasm. Other side effects include: blurred vision, lacrimation, photophobia, and xerophthalmia. Stop using this medicine if your eyes get swollen, painful, or have a discharge, and see your doctor or health care professional as soon as you can. 4.8 Undesirable effects Dorzolamide 20mg/ml Eye Drops Solution was evaluated in more than 1400 individuals in controlled and uncontrolled clinical studies. Sandoz Dorzolamide: Dorzolamide belongs to the family of medications called carbonic anhydrase inhibitors. Common side effects of … Risks and risk factors. Discontinue use if signs of hypersensitivity or a serious reaction occur. The lowest GoodRx price for the most common version of dorzolamide / timolol is around $13.75, 85% off the average retail price of $94.10. Find everything you need to know about Dorzolamide And Timolol Ophthalmic (Cosopt), including what it is used for, warnings, reviews, side effects, and interactions. Last updated on April 26, 2020. pregnancy, upcoming surgery, etc. Possible side effects such as dizziness and visual disturbances may affect the ability to drive and use machines. You may report side effects to the FDA at 1-800-FDA-1088. Dorzolamide is a sulfonamide; although administered ocularly, systemic absorption may occur and could result in hypersensitivity. It is a combination of dorzolamide hydrochloride and timolol maleate. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Along with its needed effects, a medicine may cause some unwanted effects. These side effects may go away during treatment as your body adjusts to the medicine. Get emergency medical help if you have signs of an allergic reaction … Medically reviewed by Drugs.com. This site complies with the HONcode standard for trustworthy health information: verify here. Some side effects may not be reported. O 0. Elevated intra-ocular pressure is a major risk factor in the pathogenesis of optic nerve damage and visual-field loss. Trusopt (dorzolamide) ophthalmic solution (a liquid that is placed in the eyes) is a carbonic anhydrase inhibitor used to treat glaucoma. Buy Dorzolamide Online. PRECAUTIONS: Before using dorzolamide, tell your doctor or pharmacist … Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. No information currently available. Although not all of these side effects may occur, if they do occur they may need medical attention. Although not... For … Common side effects of Trusopt … These are side effects of Trusopt (Dorzolamide) reported to the FDA by people taking it, and by doctors and pharmacists. Filter group. Do not use in pets that are allergic to it or sulfonamides. Do not use in pets that are allergic to it or sulfonamides. Common side effects include stinging sensation, eye redness, watery eyes, and light sensitivity. Although not all of these side effects may occur, if they do occur they may need medical attention. Effects begin within three hours and lasts for at least eight hours. 4.8 Undesirable effects Dorzolamide 20mg/ml Eye Drops Solution was evaluated in more than 1400 individuals in controlled and uncontrolled clinical studies. Side effects not requiring immediate medical attention Cold- or flu-like symptoms crusting or scales on eyelid dryness of the eyes indigestion or upset stomach sore throat stuffy or runny nose tearing of the eye In clinical studies, local ocular adverse effects, primarily conjunctivitis and lid reactions, were reported with chronic administration of Dorzolamide hydrochloride ophthalmic solution. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Approximately 1 in 4 patients complain of a bitter taste, and 1 in 10 patients experience an allergic eye reaction or eye inflammation (superficial punctate keratitis). You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. Ophthalmic dorzolamide may cause your eyes to become more sensitive to light than they are normally. Dorzolamide eye drops may cause side effects. This content does not have an English version. May enhance the adverse/toxic effects of other carbonic anhydrase inhibitors. ).Some health conditions may make you more susceptible to the side-effects of the drug. Stop using this medicine and call your doctor at once if you have: swelling or redness of your eyelids; sensitivity to light; or; signs of eye infection--swelling, redness, severe discomfort, crusting or drainage. Tell your doctor about the allergy and what signs you had. DORZOLAMIDE; TIMOLOL is used in the eye to treat open-angle glaucoma and high pressure in the eye. Effects begin within three hours and lasts for at least eight hours. Find everything you need to know about Dorzolamide And Timolol Ophthalmic (Cosopt), including what it is used for, warnings, reviews, side effects, and interactions. ), allergies, pre-existing diseases, and current health conditions (e.g. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Burning. If you notice any other effects, check with your healthcare professional. All drugs may cause side effects. Can dorzolamide eye drops cause problems? Based on these clinical trials, the most common side effects of dorzolamide (occurring in approximately one-third … Systemic effects: Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online, Burning, stinging, or discomfort when medicine is applied, itching, redness, swelling, or other sign of the eye or eyelid irritation, redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid, Blistering, burning, crusting, dryness, or flaking of the skin, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, sores, ulcers, or white spots in the mouth or on the lips, numbness, tingling, pain, or weakness in the hands or feet, increased sensitivity of the eyes to sunlight, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, severe redness, soreness, or swelling of the skin. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Dorzolamide is a sulfonamide and can be absorbed into the body. Common side effects of dorzolamide include burning, stinging, or discomfort of the eye after administering. Commonly reported side effects of dorzolamide ophthalmic include: burning sensation of eyes, eye discomfort, eye pruritus, local ocular hypersensitivity reaction, stinging of eyes, superficial punctate keratitis, swelling of eye, bitter taste, eye irritation, and eye redness. These side effects may go away during treatment as your body adjusts to the medicine. Dorzolamide, sold under the brand name Trusopt among others, is a medication used to treat high pressure inside the eye including glaucoma. Commonly reported side effects of dorzolamide ophthalmic include: burning sensation of eyes, eye discomfort,... For the Consumer. It is used to lower high eye pressure. Side Effects. Serious Side Effects of Dorzolamide/Timolol Some dorzolamide/timolol side effects, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. Avoid taking your pet into bright sunlight if your pet seems uncomfortable. Common Side Effects Dorzolamide has been studied thoroughly in clinical trials, in which the side effects of a group of people taking the drug are documented. Individuals who are allergic to sulfonamides may react to dorzolamide. Although not all of these side effects may occur, if they do occur they may need medical attention. This content does not have an Arabic version. Tell your doctor if any of these symptoms are severe or do not go away: stinging, burning, or discomfort in the eye after inserting the drops; bitter taste after inserting the drops; sensitivity to light; upset stomach; vomiting; Some side effects can be … Learn more about Azopt (Brinzolamide) Give as directed by your veterinarian. Stinging. What are some other side effects of Dorzolamide? Before using Dorzolamide Timolol Eye Drops, inform your doctor about your current list of medications, over the counter products (e.g. Give as directed by your veterinarian. Long-term use of Lumigan (bimatoprost) Eye swelling and inflammation. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for DORZOLAMIDE WITH TIMOLOL. Dorzolamide Side Effects. Trusopt is available in generic form. Cerner Multum, Inc. "Australian Product Information." Possible side effects such as dizziness and visual disturbances may affect the ability to drive and use machines. Dorzolamide ophthalmic Side Effects In Summary. You may report side effects to Health Canada at 1-866-234-2345. These doses represent estimated plasma Cmax levels in rats, 104 and 52 times higher than the lower limit of detection in human plasma following ocular administration, respectively. Along with its needed effects, dorzolamide ophthalmic may cause some unwanted effects.