Consult your doctor before breast-feeding. ), allergies, pre-existing diseases, and current health conditions (e.g. Important information. This product contains brimonidine and timolol. If you miss a dose, use it as soon as you remember. It works by reducing the amount of fluid in the eyes. To make sure Combigan is safe for you, tell your doctor if you have: congestive heart failure, coronary artery disease, history of stroke or blood clot; high or low blood pressure, circulation problems (such as Raynaud's syndrome); diabetes (using brimonidine and timolol ophthalmic may make it harder for you to tell when you have low blood sugar); a history of glaucoma or increased pressure inside your eye. You can save money on Combigan eye drops 0.2/0.5 % using online pharmacies. The reported Combigan eye drops prices. Consult your pharmacist or local waste disposal company.Information last revised August 2020. This combination medication is used to treat high pressure inside the eye due to glaucoma (open-angle type) or other eye diseases (e.g., ocular hypertension). COUPON (4 days ago) The most common side effects are inflammation of the eye or around the eye, eye redness, itching of the eyes, or a burning sensation of the eye. (2 days ago) Combigan Eye Drops Coupon - $50 Per Month Total Cost (3 days ago) Combigan is not safe for children under 2 years old to use. Combigan eye drops may contain a preservative that can discolor soft contact lenses. It is a combination of brimonidine (an α 2 adrenergic agonist) and timolol (a β adrenergic blocker), in concentrations of 0.2% and 0.5% respectively. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Be careful if you drive or do anything that requires you to be alert. Aspiration Hazard No information available. The recommended dose is one drop of Combigan in the affected eye(s) twice daily, approximately 12 hours apart. US residents can call their local poison control center at 1-800-222-1222. Keep using this medication even if you feel well. Hold the dropper directly over your eye and place 1 drop in the pouch, usually 2 times daily (12 hours apart) or as directed by your doctor. This medication passes into breast milk, but is unlikely to harm a nursing infant. Plasma concentrations of brimonidine peaked at 1 to 4 hours after ocular dosing. Combigan may also be used for purposes not listed in this medication guide. Use Combigan exactly as prescribed by your doctor. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If it is near the time of the next dose, skip the missed dose. Timolol is thought to work by decreasing the amount of fluid formed in the eye. To help you remember, use it at the same times each day. Selected from data included with permission and copyrighted by First Databank, Inc. Lowering eye pressure back to normal can prevent the onset of glaucoma. Both substances work by decreasing the synthesis of aqueous humor. All rights reserved. Consult your doctor for more details. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not give Combigan to a child without medical advice. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Normal volunteers dosed with one drop of COMBIGAN® twice daily in both eyes for seven days showed peak plasma brimonidine and timolol concentrations of 30 pg/mL and 400 pg/mL, respectively. Tilt your head back, look up, and pull down the lower eyelid to make a pouch. Wait at least 15 minutes after using this medicine before putting in your contact lenses. Do not start, stop, or change the dosage of any medicines without your doctor's approval. It belongs to a class of drugs known as alpha agonists. Look down and gently close your eyes for 1 to 2 minutes. Replace the dropper cap after each use. Tell your doctor right away if you have any eye injury or infection, or if you need to have any type of surgery, especially eye surgery. Timolol belongs to a class of drugs known as beta blockers. Combigan may also be used for purposes not listed in this medication guide. Properly discard this product when it is expired or no longer needed. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. If you are using another kind of eye medication (e.g., drops or ointments), wait at least 10 minutes before applying other medications. You may be advised to start using a new bottle. 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